Neurodegenerative Disorders and Injury
Neurogenetics describes the role of genetics in the development and function of the nervous system. Logarithm of odds (LOD) is a statistical technique used to evaluate the probability of gene linkage between traits. Recombinant DNA alters the genome of an organism , usually by mutation. Research has been done in model organisms like mice, Drosophila, C. elegans and. Zebrafish. Since these organisms cannot completely model the complexity of the human body, Blood, Cerebrospinal fluid, Muscle tissue samples are taken from the volunteer participants. Neurogenetic research has made possible to determine the number of gene loci that have been linked to specific diseases. Example, DR15, DQ6 have been linked to Multiple Sclerosis and LRRK2, PARK2, PARK7 have been linked to Parkinson's disease.
- Track 1-1 Repeat Expansion Diseases
- Track 2-2 Ataxias
- Track 3-3 Motor Neuron Disease
- Track 4-4 Prion diseases
- Track 5-5 Neuroimaging
- Track 6-6 Dystonia